NAD+ CellFuel™ 101: A Complete Patient Guide

• (Nicotinamide Adenine Dinucleotide Injectable)

  Your easy-to-follow guide to how NAD+ CellFuel™ works, why it matters, and how to use it safely and effectively.

  If approved, a healthcare provider on the FancyMeds platform will prescribe a compounded medication containing tirzepatide, which may also include additional metabolic support ingredients. The pharmacy that will ship to you depends on your state of residence, and each pharmacy that FancyMeds partners with has its own unique set of metabolic support ingredients, and your licensed healthcare provider may prescribe varying components to your compounded medication. Therefore, depending on the state and the individualized assessment performed by your healthcare provider, you may receive different metabolic support ingredients from the corresponding pharmacy.

• Important Safety Note

  This guide is here to help you understand NAD+ CellFuel™ and how to use it properly. It doesn’t replace the advice of your doctor. Always follow your provider’s instructions and reach out to them if anything feels off.

• What is NAD+?

  NAD+ (nicotinamide adenine dinucleotide) is a molecule found in every cell in your body. You need it to stay alive — your cells use it to create energy, repair damage, and keep things running smoothly.

  But as you age, your natural NAD+ levels drop — and that can lead to fatigue, brain fog, slower recovery, and a general feeling of being “off.” NAD+ CellFuel™ is an injectable version of this molecule that helps replenish those levels and get your cells working at full strength again.

  NAD+ plays several important roles in the body:

  • Boosting energy by helping your cells make ATP (their fuel)

  • Repairing DNA that’s been damaged over time

  • Activating longevity enzymes like sirtuins that help fight aging and inflammation

  
  

  📚 References:

  Conlon NJ (2022). The Role of NAD+ in Regenerative Medicine.

  Braidy N et al. (2019). NAD+ as a Therapeutic Target for Age-Related Diseases.

• Why Has It Been Prescribed to Me?

  Your healthcare provider may have recommended NAD+ CellFuel™ if you:

  • Feel tired all the time, even after rest

  • Are struggling with mental clarity or focus

  • Have a hard time recovering from workouts or illness

  • Are interested in supporting long-term health and aging

  This treatment gives your body the NAD+ it needs to repair itself, make energy more efficiently, and help you feel more alert, active, and focused.

  
  

• How Does It Work?

  Think of NAD+ as the fuel your cells use to do their job. It’s especially important for the mitochondria — the part of the cell that makes energy. NAD+ also helps fix damaged DNA and activates proteins that keep cells young and healthy.

  With age or chronic stress, your body may not make enough NAD+ on its own. NAD+ CellFuel™ delivers it through a tiny injection under the skin so your body can absorb it quickly and use it where it’s needed.

• How Do I Use It?

  Your 2-Month NAD+ CellFuel™ Plan:

  Weeks 1–4: Ramp-Up Phase

  • Inject under the skin into the fatty tissue layer

  • Start with a smaller dose and increase gradually each week (your provider will guide you)

  • Inject in the morning on an empty stomach

  • Alternate injection sites (abdomen and thighs work best)

  Weeks 5–8: Maintenance Phase

  • Keep injecting three times a week

  • Stick with your steady dose as advised

  • This phase is all about keeping your NAD+ levels strong and consistent

  💡 Tip: Don’t inject more or less than your provider recommends. If you miss a dose, skip it and stay on schedule.

• Storage and Handling

  • Keep your vials in the fridge: 36–46°F (2–8°C)

  • Do not freeze

  • Dispose of used syringes in a sharps container

  • Keep out of reach of children

  
  

• Are There Any Side Effects?

  Most people feel great on NAD+, but some report:

  • Mild headache

  • Slight nausea

  • Redness or tightness where they injected

  • A brief feeling of muscle tension or warmth

  These usually go away quickly. If anything feels unusual or doesn’t go away, contact your provider.

  🚫 Don’t use NAD+ CellFuel if:

  • You are pregnant or breastfeeding (unless approved by your doctor)

  • You have a history of cancer (talk to your provider first)

  • You’ve had a reaction to NAD+ or its ingredients in the past

• What Results Can I Expect?

  Everyone’s different, but here’s what many people report:

  1–2 Weeks:

  • More energy

  • Clearer thinking

  3–6 Weeks:

  • Better recovery

  • Improved mood and sleep

  6–8 Weeks and Beyond:

  • A general feeling of being more “on”

  • Long-term support for aging, inflammation, and metabolism

  Remember: consistency matters. Skipping doses may slow your results.

• Can I Combine NAD+ CellFuel™ with Other Medications?

  Yes — NAD+ therapy is one of the most versatile and safe injectable treatments, and it’s commonly used alongside other peptides and medications to enhance overall wellness, performance, and recovery.

  
  

  ✅ Safe and Effective Combinations:

  • Sermorelin (AgeDefy™) - Sermorelin stimulates natural growth hormone production, while NAD+ enhances mitochondrial energy and cellular repair. Together, they form a synergistic combo that supports sleep, metabolism, tissue recovery, and healthy aging.

  📚 References:

  Walker RF et al., 2001 – Growth hormone-releasing peptides in aging (PubMed)

  Braidy N et al., 2019 – NAD+ in aging and neurodegeneration (NCBI)

  • PT-141 (PassionFuel / Arouse) - NAD+ helps support mood, energy, and neural function, while PT-141 boosts sexual desire via melanocortin pathways. These can be used in tandem, particularly for patients experiencing libido or performance concerns due to fatigue or brain fog.

  📚 References:

  Shadiack AM et al., 2007 – PT-141 and sexual response (PubMed)

  • GHK-Cu (SkinRevive™) - NAD+ supports DNA repair and cellular rejuvenation internally, while GHK-Cu promotes collagen production and wound healing on the surface. Used together, they may improve skin tone, elasticity, and anti-aging outcomes.

  📚 References:

  Pickart L, 2008 – GHK-Cu in skin remodeling (PubMed)

  Braidy N et al., 2019 – NAD+ and skin health (NCBI)

  ⚠️ Use With Clinical Oversight:

  • Semaglutide / Tirzepatide (GLP-1 Medications) - There are no known negative interactions between NAD+ and GLP-1 medications. In fact, many users on Semaglutide or Tirzepatide report fatigue, slowed metabolism, or brain fog — symptoms NAD+ can help offset by boosting mitochondrial function. However:
  • GLP-1s slow gastric emptying, so timing of NAD+ may matter (best injected on an empty stomach)
  • Low calorie intake may reduce cellular NAD+ synthesis — making supplementation especially beneficial

  📚 References:

  Nauck MA et al., 2021 – GLP-1 agonist effects (NEJM)

  Verdin E, 2015 – NAD+ and metabolic regulation (Cell Metabolism)

  • Glutathione - These two are highly complementary. NAD+ plays a direct role in regenerating reduced glutathione (GSH), the body’s master antioxidant. When used together, they offer powerful protection against oxidative stress, improve detoxification, and promote longevity.

  📚 References:

  Wu G et al., 2004 – Glutathione metabolism and antioxidant functions (NCBI)

  Richie JP et al., 2015 – Glutathione supplementation study (PubMed)

• Final Word

  NAD+ is a foundational molecule for energy, repair, and aging — and combining it with other FancyMeds therapies can amplify your results.

  That said, every treatment plan should be personalized. Your provider will review your health history and help you build the right stack for your goals.