PT-141 PassionShot™: Patient Guide

• (Bremelanotide Injectable Peptide Therapy)

• Important Safety Note

  This guide is for educational purposes only and does not replace medical advice. Always follow your licensed provider’s instructions and contact your provider with questions.

• What is PT-141 PassionShot™?

  PT-141 (bremelanotide) is a prescription injectable peptide that may be considered for certain adults experiencing low sexual desire. It works through pathways in the brain rather than by replacing hormones.

  It is a non-hormonal treatment option that may be considered based on your medical history, symptoms, and provider evaluation.

  Bremelanotide has been studied in women with acquired, generalized low sexual desire. A licensed provider can help determine whether treatment is appropriate based on your individual history and symptoms.

• Who is it for?

  PT-141 may be considered for certain adults who:

  • Have concerns related to low sexual desire

  • Are interested in discussing non-hormonal treatment options with a licensed provider

  • Want a provider-guided evaluation to determine whether treatment is appropriate

  Treatment decisions should be based on an individual medical review, including symptoms, health history, and treatment goals.

• How Does It Work?

  PT-141 works through melanocortin receptors in the brain, which play a role in sexual desire. Unlike hormone-based approaches, it acts through central nervous system pathways. A licensed provider can help determine whether it may be appropriate for your needs.

• How to Use PT-141

  PT-141 is a subcutaneous injection prescribed on an individual basis. Your provider will determine how and when it should be used based on your treatment plan.

  General Use Information:

  • Use only as prescribed by your provider

  • Follow the timing and frequency instructions included with your treatment

  • Use the provided supplies for administration

  • Reach out to your provider if you have questions about use

  Your provider will tailor treatment instructions to your individual needs and goals.

• What’s Included in Your Kit?

  • PT-141 multi-dose vial(s) compounded in the USA
  • Syringes and alcohol swabs
  • Self-injection instructions
  • Provider review and prescription if approved
  • Discreet, tracked shipping
  • Support from the care team

• What Results Can I Expect?

  Response to PT-141 varies by patient. Your provider can help set expectations and determine whether treatment remains appropriate based on your medical history, symptoms, and follow-up review.

  Some patients may notice changes sooner than others, while some may require ongoing provider evaluation to determine whether treatment should continue.

• Potential Side Effects

  PT-141 may cause side effects. Possible side effects include:

  • Nausea

  • Headache

  • Flushing

  • Temporary increases in blood pressure

  If side effects are persistent, severe, or concerning, contact your provider.

• When NOT to Use PT-141:

  PT-141 may not be appropriate for everyone. Tell your provider before starting treatment if you:

  • Are pregnant or breastfeeding

  • Have uncontrolled high blood pressure

  • Have had a recent stroke or heart attack

  • Are allergic to bremelanotide or any ingredient in the formulation

  Always consult your provider before starting treatment if you have a chronic condition or take other medications.

• Can PT-141 Be Combined with Other Medications?

  PT-141 may not be appropriate to use with every medication, supplement, or therapy. Your licensed provider should review all current treatments before prescribing PT-141.

  Some patients may already be using other therapies, but any combination should be evaluated based on individual medical history, side effects, and treatment goals.

  Examples Your Provider May Review Include:

  NAD+

  If you use NAD+, include it in your intake so your provider can evaluate your overall treatment plan.

  Sermorelin

  If you are currently using sermorelin or other hormone-related therapies, your provider should review them before determining whether PT-141 is appropriate.

  GHK-Cu

  Tell your provider about any peptide therapies or injectables you are using so they can review your current regimen.

  Semaglutide or Tirzepatide (GLP-1 Medications)

  If you use a GLP-1 medication, your provider should review side effects, cardiovascular history, and other relevant health factors before starting PT-141.

  Glutathione

  If you are using glutathione or other supportive therapies, include them in your medical intake for provider review.

  Important Note

  Do not combine prescription treatments without provider guidance. A licensed provider should determine whether PT-141 is appropriate based on your full health history and current therapies.

• Final Word

  PT-141 can be a powerful addition to your wellness protocol. If you’re using it alongside energy, hormone, or skin treatments, it’s generally safe — but combining therapies should be guided by your health history and treatment goals.

  Need help building the right stack? Our provider team can tailor a personalized plan for you. 💬